Huseyin Karaburk - University of Michigan

Completed BS and MSc with high honor Recipient of the following grants/awards: University of Michigan Rackham Precandidate Graduate Student Research Grant (2022) University of Michigan Rackham Conference Travel Grant (2022) ASCB Travel Grant for LGBTQ+ community members (2022) ASCB Travel Grant for US-based graduate students (2022) LSI Cubed Research Grant (2024) University of Michigan Rackham Conference Travel Grant (2024) David and Michelle Kroin Family Scholarship Fund (2024) Sarah Winans Newman Graduate Student Teaching Award at University of Michigan (2025) Published following papers: Kocakaplan, D*., Karabürk, H*., Dilege, C., Kirdök, I., Bektas, S. N., & Caydasi, A. K. (2021). Protein phosphatase 1 in association with Bud14 inhibits mitotic exit in Saccharomyces cerevisiae. ELife, 10. https://doi.org/10.7554/elife.72833 Cheng C., Hu J., Mannan R., He T., Bhattacharyya R., Magnuson B., Wisniewski JP., Peters S, Karim SA., MacLean DJ., Karabürk H., Zhang L., Rossiter NJ., Zheng Y., Xiao L., Li C., Awad D., Mahapatra S., Bao Y., Zhang Y., Cao X., Wang Z., Mehra R., Morlacchi P., Sahai V., Pasca di Magliano M., Shah YM., Weisman LS., Morton JP., Ding K., Qiao Y., Lyssiotis CA., Chinnaiyan AM (2025).  Targeting PIKfyve-driven lipid homeostasis as a metabolic vulnerabilityin pancreatic cancer. Nature, 10.1038/s41586-025-08917-z In press/to be submitted papers: Zheng Y., Cheng C., Cao Y., Cruz G., Zhang Y., Paturu R., Mahapatra S., Hu J., Mannan R., Karabürk H, Bhattacharyya R., Yin Y., Cao X., Xue H., Li C., Wang Z., Miner SJ ., Vaishampayan U., Sahai V., Weisman LS., Ding K., Lyssiotis CA., Wang Y., Qiao Y., Chinnaiyan AM (2026). Stress-Defined Dependency on PIKfyve Creates a Therapeutic Vulnerability in Neuroendocrine Prostate Cancer. Cancer Cell (submitted) Luo G*.., Karabürk, H*., Kreider-Letterman G., Reyes-Ordoñez A., Rivero-Rios P., Deng Y., Kovarzin A., Kumar GA., Lee YC., Benyair R., Chen S., Bristow E., Mucci CA., Ma X., Shree S., Sligar SG., Puthenveendu MA., Nesvizhskii AI., Parent CA., Chen J., Garcia-Mata R., Weisman LS (2026). PIKfyve promotes cell migration through Kindlin-2, a RAC1 activator, and ARHGAP17, a negative regulator of RAC1. Plos Biology (to be submitted) * these authors contributed equally